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Disorders of the temporomandibular joint (TMJ) are widespread, afflicting between 5 and 40 percent of the adult population. TMJ disorder (TMJD) encompasses several conditions including orofacial pain, restricted mandibular movement, clicking and popping sounds from the jaw joint, and locked jaws. About 10 to 15 percent of TMJD patients have osteoarthritis, characterized by a degenerative joint which results from erosion of articular cartilage and degeneration of subchondral cortical and trabecular bone. Symptoms can become chronic and difficult to manage, severely reducing quality of life.

Southwest Research Institute
Daniel P. Nicolella, Ph.D.; Jessica Coogan

The outcomes of this research project provide opportunities to overcomes some of the challenges in successful translation of animal data into practical applications for humans such as predicting TBI and developing appropriate design criteria for impact sensor technology and protective equipment. In this project. we also develop axonal injury thresholds for repeated TBI for the first time. 
 
 
 Abstract: 
 Traumatic brain injury (TBI). particularly mild-TBI/ concussion.

The University of Texas at San Antonio
Hajiaghamemar, Marzieh