As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Bavarian Nordic A/S
The objective is to perform and report on human FV Challenge studies in NHP cohorts using an IM injection of approximately 1000 pfu/animal USG-designated, well-characterized human Filoviruses.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Anderson, Timothy J. C.
Funded by
NIH-PMS
Collaborating Institutions
University of Notre Dame
Columbia University
Artemisinin combination therapy (ACT) is the main treatment for Plasmodium falciparum malaria: the success of this treatment has rolled back malaria and renewed interest in malaria elimination. Slow clearance of parasites following ACT treatment of patients in SE Asia has lead to concern about the spread of resistance. This proposal aims to identify the genes that underlie slow clearance to better understand the evolution and biochemical basis of his trait.
Naval Medical Research Unit San Antonio (NAMRU-SA)
Located in South Texas on the San Antonio, Military Joint Base complex, the Naval Medical Research Unit San Antonio (NAMRU-SA) is one of eight subordinate research commands in the global network of laboratories operating under the Naval Medical Research Center, Silver Spring, MD.
Principal Investigator(s)
John Simecek, D.D.S., M.P.H.
Funded by
U.S. Navy Bureau of Medicine and Surgery (BUMED) http://www.med.navy.mil/Pages/Default.aspx
Bacterial infection is a frequent complication among trauma and surgical patients, both civilian and military. The rate of infectious complications in the U. S. military is approximately 35 percent for combat casualties. The lack of a rapid diagnostic platform for the detection of bacterial and fungal infections in combat wounds result in mortality and extended stays in Intensive Care Units. The methods currently available are time consuming, lack sensitivity, require specialized equipment, and highly trained personnel.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
Microbiotix
Ebola virus causes highly lethal viral hemorrhagic fever syndrome and has been classified as a Category A bioweapons agents by the Centers for Disease Control and Prevention (CDC). It can be used as a potential biological weapon due to their ease of dissemination, person-to person transmissibility and stability in aerosolized form. There is no effective vaccine or antivirals against Ebola virus infection in humans.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
The Regents of the University of CA
This project is a novel approach to detecting and identifying viruses rapidly and quantitatively on a compact, portable platform suitable for point-of-care diagnostics. The proposed optofluidic platform would impact public health in a number of ways, including screening for outbreaks of biodefense and emerging pathogens, rapid decision making in patient diagnosis, or continuing viral load monitoring for disease management.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Patterson, Jean L.
Funded by
Emory University
Filoviruses are etiologic agents that cause highly lethal hemorrhagic fevers and can be transmitted via person-to-person contact, thus posing a high threat to public health. We have recently demonstrated the combined benefit of two non-viral-vector based vaccine platforms and its potential for the development of an efficacious vaccine against EBOV infection.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Carrion, Ricardo
Funded by
Lovelace Biomedical & Environmental Research Inst
The purpose of this project is the test Filovirus vaccines for their immunogenicity and efficacy in NHP cohorts.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Hernandez, Javier
Funded by
NIH
Prostate cancer is the most common non-dermatologic neoplasm in men, affecting about one man in six in his lifetime. The primary public health approach for control of this disease is currently early diagnosis and treatment, relying primarily on the Prostate Specific Antigen (PSA) blood test for detection. Unfortunately, for most men with a PSA above 4.0 ng/mL (the most commonly-applied upper limit of normal), no prostate cancer is found at biopsy while many cancers are found below this 'normal' level.