The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Lamb, Audrey
Funded by
Natl Science Fdn
This research project will be undertaken to define the structure-function relationships of the enzymes of riboflavin biosynthesis.Riboflavin biosynthesis includes five enzymatic activities that are unparalleled in nature. This pathway has been studied in sufficient detail to establish the chemical transformations performed by each enzyme and the salient characteristics of the enzymes. The focus of this proposal is the mechanisms of the unusual deformylation reactions of RibA and RibB and the unconventional multi-activity of RibD will be defined.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Turner, Joanne
Core instrumentation for the Biology Core to expand the flow cytometry capabilities.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Schlesinger, Larry S
Funded by
Kronkosky Charitable Foundation
The purpose of this grant is for the purchase of a Confocal Microscope for Core Research Support project.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Daadi, Marcel M
Funded by
National Institutes of Health
The overarching goal of this proposal is to establish the baboon as a relevant model of age-related cognitive impairment by validating behavioral, cognitive, and neuroanatomical features affected in aged baboons and identifying the appropriate miRNA biomarkers that may be causal of the age-related structural and functional changes.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Schlesinger, Larry S
Funded by
National Institutes of Health
The major goal is to increase primate holding capacity for the P51 base grant.
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Leopold Wager, Chrissy M
M. tuberculosis, which causes the worldwide global health problem tuberculosis (TB), is transmitted human to human via the airborne route into lung alveoli and ultimately exploits and grows in host macrophages. We seek to understand the cell signaling pathways initiated by infection of human macrophages with M. tuberculosis that lead to disease. Increased understanding of how macrophages are susceptible to M. tuberculosis is expected to aid in the development of host-directed therapies for TB.
The University of Texas at San Antonio is an emerging Tier One research institution with nearly 29,000 students.
Principal Investigator(s)
Perry, George
Plascencia Villa, German
Funded by
Univ of TX HSC at Houston 744
Alzheimer's disease (AD) is increasing in number as the U.S. and global population gets older. Despite enormous effort and expense. treatment remains at best modestly effective and no new drugs have been approved since 2003 [1.2]. The increasing interest in drug discovery through repositioning old drugs for new therapeutic applications throw light in the treatment for neurodegenerative diseases including AD [3].
As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.
Principal Investigator(s)
Ebrahimi, Diako
Collaborating Institutions
University of Texas Health Science Center San Antonio
We aim to fully characterize mutational signatures of SARS-CoV-19 focusing on the furin cleavage site, determine the role of the GC-rich sequence and CpG sites within the furin cleavage site and develop neutralizing Abs to target the furin cleavage site.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Musi, Nicolas
For the past three decades, the University of Texas Health Science Center at San Antonio (UTHSCSA) hashosted a premier Training Program in the biology of aging that has resulted in the development of a newgeneration of leaders in this field. This application seeks to continue this T32 Training Program and we requestfunds to support four predoctoral and four postdoctoral trainees.