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San Antonio Medical Foundation

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The major goal of this project, using a model of Kawasaki disease in mice, is to selectively turn off the FSTL-1 gene at different times during the onset and development of the disease, and evaluate if, and how, FSTL-1 affects the heart damage seen in Kawasaki disease in order to develop an effective treatment strategy for Kawasaki disease's long term effects.

Texas Biomedical Research Institute
Patterson, Jean

This study is a prospective multicenter double-blind randomized controlled trial. It will recruit patients with SCAF (Sub-Clinical Atrial Fibrillation) detected by either a pacemaker, an ICD (implantable cardioverter defibrillator) or an insertable cardiac monitor (ICM); who also have other risk factors for stroke (previous stroke/TIA or systemic arterial embolism OR age ? 75 OR age 65-74 with ? 2 other risk factors OR age 55-64 with ? 3 other risk factors). Eligible and consenting patients will be randomized to receive aspirin or apixaban.

Brooke Army Medical Center
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