This is a randomized, double-blind, placebo-controlled phase 3 study designed to compare the OS between patients treated with HMA plus vadastuximab talirine (experimental arm) versus patients treated with HMA plus placebo (comparator arm). Patients will be randomized in a 1:1 manner to one of the study arms. Investigators may select either HMA (azacitidine or decitabine).
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The University of Texas at San Antonio
The University of Texas at San Antonio
Southwest Research Institute
Southwest Research Institute
The University of Texas at San Antonio
The University of Texas at San Antonio