Facilitated By

San Antonio Medical Foundation

Ketamine For Antidepressant-Resistant PTSD

Brooke Army Medical Center

Brooke Army Medical Center (BAMC) at Fort Sam Houston, Texas, is proud to provide safe, quality care to our military service members, their families, veterans and civilian emergency patients as the most robust and productive healthcare organization within the Military Health System (MHS).

Principal Investigator(s)
Email for information
Funded by
UTHSCSA
Research Start Date
Status
Active

This randomized clinical trial proposes to consent 240 Veterans and active-duty military personnel with antidepressant-resistant posttraumatic stress disorder (PTSD) at two sites (VA Connecticut Healthcare System, West Haven Campus and the San Antonio Military Medical Center; SAMMC) to test the safety and efficacy of repeated doses of intravenously administered ketamine as compared to placebo, in reducing symptoms of PTSD. At SAMMC, up to 120 active duty military personnel will be consented to randomize 99 and obtain complete data on 80 for analysis. After consent and screening, eligible individuals will be randomized to one of three treatment groups to receive placebo, ketamine 0.2 mg/kg, or ketamine 0.5 mg/kg.

Clinical Care
Behavioral Health
The appearance of name-brand products in this article does not constitute endorsement by Brooke Army Medical Center, the U.S. Army Medical Center, the U.S. Army Medical Department, the U.S. Army Office of the Surgeon General, the Department of the Army, the Department of Defense, or the U.S. Government of the information, products, or services contained therein.