The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Casali, Paolo
Funded by
NIH-ALLERGY & INFECTIOUS DISEASES
This T32 application seeks support for a Graduate Research in Immunology Program (GRIP) at the University of Texas Health Science Center San Antonio (UTHealthSA). GRIP will train three PhD, DDS/PhD and MD/PhD students per year for successful careers in academia, industry or government.
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Stockand, James David
Funded by
NIH-DIABETES/DIGESTIVE/KIDNEY DISEASES
Discretionary control of renal Na+ transport matches renal Na+ excretion with dietary Na+ intake. Because Na+excretion can influence blood pressure, disordered renal Na+ transport in many instances causes abnormalblood pressure. Moreover, as we know from the actions of most diuretics and many tubulopathies interdictionof normal renal Na+ transport changes blood pressure. Renal sodium excretion is fine-tuned in response tohormonal signaling in the aldosterone-sensitive distal nephron (ASDN).
The UT Health San Antonio, with missions of teaching, research and healing, is one of the country’s leading health sciences universities.
Principal Investigator(s)
Muniswamy, Madesh
Funded by
NIH-HEART LUNG & BLOOD INSTITUTE
Aberrant intracellular calcium ([Ca2+]i) homeostasis has been implicated in cardiovascular diseases (CVD) which contributes to endothelial dysfunction. Ca2+ acts as a second messenger and is known to regulate several cell functions. Despite the available evidence of a link between Ca2+ signaling and endothelial dysfunction, mechanisms underlying the development of vascular disease remain incompletely understood. Besides Ca2+, reactive oxygen species have also been implicated in endothelial cell (EC) dysfunction.
