Facilitated By

San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

Brain Health Consortium Seed Grant (Bryan Fowler): Vagal Innervation of the Stomach and Duodenum

Brain Health Topic:
 Vagal signaling between the gut and the CNS contributes to appetite regulation. inflammation and immune
 responses. gastrointestinal motility. nausea. emesis. and even mood1-6
 . Therefore. vagal neurons are an
 attractive target for medical interventions. Since vagal signaling may be modulated within the digestive tract.
 drugs need not cross the blood-brain barrier. reducing potential side effects and toxicity. To eventually identify
 potentially drug-able targets within the vagus to improve mental and digestive health.

The University of Texas at San Antonio
Macpherson, Lindsey
More Info
Fabrication of an Innovative Nanopore Microneedle for Controlled Electroporation and Gene Transfection

A significant challenge for in vivo genetic engineering is the transmembrane transport of relatively large genetic payloads. Larger molecules and transcription plasmids typically require viral vectors or permeabilizing agents. which can be challenging to engineer and may have deleterious systemic effects. As an alternative approach. electroporation uses ultrashort electrical pulses to transport large molecules across cell membranes. This approach is advantageous in applications such as delivery of DNA vaccines.

The University of Texas at San Antonio
Hood, Robert; Ahn, Ethan
More Info