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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

EVALUATION OF THE SAFETY, TOLERABILITY, EFFICACY AND ACTIVITY OF AMX0035, A FIXED COMBINATION OF PHENYLBUTYRATE (PB) AND TAUROURSODEOXYCHOLIC ACID (TUDCA), FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
UT Health San Antonio
Jackson, Carlayne E
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INTERACTION OF THE TMEM127 TUMOR SUPPRESSOR WITH THE MTORC1 LYSOSOMAL ACTIVATING COMPLEX

The mTORC1 pathway regulates multiple cellular processes to promote a switch from catabolic toanabolic metabolism and is thus under tight regulatory control by growth factor signaling and nutrientsensing pathways. Dysregulation of this complex machinery is implicated in many cancers, so definingthe key mechanisms by which mTORC1 senses changes in cellular homeostasis to activate growthsignals is of great relevance. Spatial regulation of mTORC1 signaling has been recognized as a majormechanism that influences the cellular response to nutrients and the lysosome is central to thisprocess.

UT Health San Antonio
Dahia, Patricia L
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