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Top viewed research performed by San Antonio Bioscience Organizations

Comparative Performance Analysis of Excitus AS Portable Suction Device Prototype

1.SCOPE.This research project processes experimental testing and characterization of suction devices for Excitus AS by Dr. R. Lyle Hood of the Mechanical Engineering Department at the University of Texas at San Antonio (UTSA) and Robert De Lorenzo of the Emergency Medicine Department at the University of Texas Health Science Center in San Antonio.

The University of Texas at San Antonio
Hood, Robert
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Targeting Tryptophan Dioxygenase Degradation for Suppression of Tumor Immune Evasion

The tryptophan degradation pathway is used to prevent unrestrained immune activation in healthy cells. However. tumors hijack this mechanism to escape immune surveillance. The key enzyme of this pathway. tryptophan 2.3-dioxygenase (TDO) and indoleamine 2.3-dioxygenase (IDO). are established immune checkpoint proteins. Tumors enhance their expression to block T cell proliferation and induce T cell death. thereby avoiding immune system surveillance and increasing tumor cell migration capacity. Thus.

The University of Texas at San Antonio
Liu, Aimin
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