Infectious diseases pose a significant public health burden, accounting for nearly one-fifth of deaths globallyper annum. Most infections are initiated from a restricted mucosal tissue, such as the intestine. To fightintestinal infections, gut-resident immune cells are superior to circulating ones. There is a surge of recentinterest in tissue-resident memory T (TRM) cells that have been shown to be a critical adaptive immunecomponent of mucosal immunity. These cells have been flagged as an ideal cell population to be generated inT cell-based vaccines.
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The University of Texas at San Antonio
The University of Texas at San Antonio
Southwest Research Institute
Southwest Research Institute
The University of Texas at San Antonio
The University of Texas at San Antonio