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The extensive genetic variability in seasonal and potentially pandemic influenza strains necessitates new vaccine strategies that can focus the immune response on generating protective antibodies against conserved targets such as regions within the influenza neuraminidase protein. We have demonstrated that seasonal immunization stimulates neuraminidase specific antibodies in humans that are broad and potent in their protection from influenza when tested in animals.

Texas Biomedical Research Institute
Martinez-Sobrido, Luis

Glaucoma, a leading cause of irreversible blindness in the world, is characterized by progressive degeneration of the retinal ganglion cells (RGCs), the retinal nerve fiber layer, and the optic nerve. Glaucoma is often associated with elevated intraocular pressure (IOP), and because the increased IOP exerts a compressing force on the blood vessels in the eye, it has long been hypothesized that the RGC damage is caused by mild, but chronic, reduction of basal blood flow and/or blood-flow dysregulation.

UT Health San Antonio
Duong, Timothy Q.