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Combat-incurred craniomaxillofacial injuries often result in massive bone tissue loss. Standards of care such as autologous grafting have limitations including cost, availability and prolonged inpatient care.  Thus, therapeutics are needed which can not only accelerate bone regeneration, but are also readily available, cost-effective and reduce time of inpatient care.  Amnion-derived multipotent progenitor (AMP) cells secrete a variety of cytokines and growth factors which have been shown to promote bone growth.

Naval Medical Research Unit San Antonio (NAMRU-SA)
CDR Forest R. Sheppard, MD FACS, U.S. Navy