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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

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Top viewed research performed by San Antonio Bioscience Organizations

Development of in vitro disease-relevant strains of tau

This research project will compare the strains we generate with those we purify from AD and AD related neurodegenerative disorders such as progressive supranuclear palsy. If we are successful in identifying an artificial disease-relevant strain. we will continue our screening efforts to identify disease-relevant tau aggregation inhibitors while simultaneously working toward building a library of tau aggregate strains for multiple neurodegenerative tauopathies. These efforts will not only greatly increase the probability of generating effective therapeutics.

The University of Texas at San Antonio
Gamblin, Truman
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SUMATRIPTAN AND MOH: DIFFERENTIAL 5-HT1R SIGNALING IN TRIGEMINAL NOCICEPTORS

Migraine is a collection of neurological symptoms that include recurring, intense, throbbing headache pain thatcan last from 4 to 72 hours and affects millions of people. The discovery of the triptan drugs was a majorbreakthrough for the treatment of debilitating pain for many migraine sufferers. Unfortunately, repeated orprolonged use of triptans and other analgesic drugs (e.g. opioids, ergotamines) often results in production of aserious, disabling adverse effect known as medication overuse headache (MOH).

UT Health San Antonio
Berg, Kelly A
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