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San Antonio Medical Foundation

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OVERVIEW.The objective of the proposed research project is to evolve catalytic cycloaddition reactions that originate through metallovinylcarbene [3+n]-cycloaddition processes in new directions. We will develop transformations made possible with [3+n]-cycloaddition products. will advance Br??nsted acid catalyzed cycloaddition reactions for efficient. previously unattainable molecular constructions. and will use novel chiral donor-acceptor (D-A) cyclopropanes for cycloaddition that occurs with retention of configuration.

The University of Texas at San Antonio
Doyle, Michael