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The `opioid epidemic' is one of the most significant health issues facing this country today with rates of opioid-associated deaths up 200% since 2000. This epidemic is also taking its toll on pregnant women and their babies, with an annual average of ~21,000 pregnant women ages 15 to 44 who have misused opioids this past month.  Infants who have been exposed to opioid drugs  exhibit an increased risk of neurological and behavioral consequences.

The University of Texas at San Antonio
Hsieh, Jenny

Ion channel currents are the fundamental units of electrical activity in most organisms. In our nervous system, K+ and Ca2+ channels are critical, and their regulation provides a way to directly control neuronal excitability and release of neurotransmitter (NT) at synapses. The modulations are crucial to basic nervous function and their understanding should contribute to novel modes of medical interventions for a range of disorders involving the brain, nerves and muscles.

UT Health San Antonio
Shapiro, Mark S