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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

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Top viewed research performed by San Antonio Bioscience Organizations

INTRINSIC B CELL EPIGENETIC MEDIATORS AS THERAPEUTIC TARGETS IN LUPUS
UT Health San Antonio
Casali, Paolo
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B7-H1 Signaling in Ovarian Cancer

Project Summary. We have shown that regulatory T cells (Tregs) defeat anti-cancer immunity and that their depletion can be therapeutic, but their rapid regeneration is problematic. This project uses our discoveries that B7-H1 immune co-signaling facilitates Treg generation and that estrogen receptor (ER)? signals inhibit Treg regeneration in relevant pre-clinical mouse models with proven substantial translational relevance.

UT Health San Antonio
Curiel, Tyler J.
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