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Ebola virus causes highly lethal viral hemorrhagic fever syndrome and has been classified as a Category A bioweapons agents by the Centers for Disease Control and Prevention (CDC). It can be used as a potential biological weapon due to their ease of dissemination, person-to person transmissibility and stability in aerosolized form. There is no effective vaccine or antivirals against Ebola virus infection in humans.

Texas Biomedical Research Institute
Patterson, Jean L.

Inhibition of the renal SGLT2 transporter has proven to be an effective therapeutic interventionto reduce plasma glucose levels and HbA1c in type 2 diabetic patients. The glycemic-loweringefficacy of the SGLT2 inhibitors results from two distinct mechanisms: (i) induction ofglucosuria, which amounts to ~70-90 grams per day and (ii) amelioration of glucotoxicity leadingto increased insulin sensitivity in muscle and improved beta cell function (JCI 124:509-514,2014).

UT Health San Antonio
DeFronzo, Ralph A