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San Antonio Medical Foundation

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The purposes of the study are as follows: 1) to test the development of a potential anticancer study called E39 peptide vaccine and J65 peptide vaccine; 2) to determine if the study vaccine is safe; 3) to determine the best dose of the study vaccine 4) to learn more about the side effects of the study vaccine and how it affects the immune system; and 5) to determine if folate binding protein expression in tumor is associated with the effectiveness of the vaccine.

Cancer Insight, LLC
George Peoples

Gene copy number variation (CNV) is ubiquitous in eukaryotic genomes and the resultant dosage changes can play an important role in determining phenotype. We aim to define the extent, evolutionary dynamics and functionality of CNV in the malaria parasite genome (Plasmodium falciparum). To achieve this we will use comparative genomic hybridization (cGH) which provides an efficient tool for assaying both CNV and single nucleotide polymorphism (SNP) and is particularly effective in haploid genomes.

Texas Biomedical Research Institute
Anderson, Timothy J. C.