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San Antonio Medical Foundation

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The objective is to perform and report on human FV Challenge studies in NHP cohorts using an IM injection of approximately 1000 pfu/animal USG-designated, well-characterized human Filoviruses.

Texas Biomedical Research Institute
Carrion, Ricardo

There is a continual need to explore alternative approaches to treat cancer to improve patient outcome and reduce the dreadful side-effects of some of the therapies available. While specific bacteria have shown a natural propensity to target tumors in animal models and have been engineered for drug delivery, targeting in human trials was essentially ineffective. To date, while antibody based targeting has been employed to deliver radio- or chemo- active compounds to destroy the tumor, it has so far not been fully explored to deliver bacteria.

Texas Biomedical Research Institute
Hayhurst, Andrew