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Novel model for studying PDAC using normal human pancreatic tissue For the past twenty years, the survival rate for many cancers has improved, but survival for pancreaticductal adenocarcinoma (PDAC) has not, due to lack of both early detection methods and effective treatments.Human PADC cancer cell lines have been widely used. However, such cell lines are far from original organtissue, and their highly unstable genome complicates interpretation.

UT Health San Antonio
Wang, Pei

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide, accounting for approximately 18% of all cancer deaths.1 Despite treatment with platinum-based chemotherapy, the standard of care for first-line therapy, patients with metastatic NSCLC have a median survival of approximately 10 months, and a 5-year survival rate of less than 5%. Immunotherapeutic approaches have demonstrated clinical efficacy in several cancer types, including melanoma, hormone-refractory prostate cancer, and lung cancer.3,4.

Brooke Army Medical Center
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