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San Antonio Medical Foundation

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Nowadays, much of our daily work is performed indoors and indoor environment can significantly affect human performance [1]. It is estimated that improving indoor environment in US office buildings would result in a 0.5% to 5% increase in productivity, worth $12 - $125 billion annually [3]. Among many indoor environmental factors, thermal environment is one of the most important factors that impact human performance. Inadequate thermal conditions of being either too cold or too warm have been shown to lead >8% reduction of peak performance [4].

The University of Texas at San Antonio
Huang, Yufei; Hsieh, Jenny

Frailty is a geriatric syndrome which leads to poor health outcomes in older adults, such as falls, disability,hospitalization, institutionalization, and death. Due to the dramatic growth in the U.S. aging population and thehealth care costs associated with frailty (estimated at more than $18 billion per year), frailty is a major healthcare problem. There has been little research into potential pharmacologic interventions that would delay orreduce the incidence of frailty. Thus, the major goal of this study is to test metformin as a novel intervention forthe prevention of frailty.

UT Health San Antonio
Espinoza, Sara E