Several clinically unrelated neurodegenerative disorders, termed conformational diseases, are character-ized by a common pathophysiology that involves aggregation and accumulation of misfolded proteins. All ofthese diseases activate cell stress signaling pathways, mainly the endoplasmic reticulum (ER) stress-inducedunfolded protein response (UPR) pathway. In particular, the proximal UPR kinase, PERK, is abnormally activein Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP) and Frontal Temporal Dementia (FTD)-affected brain regions.
A Collaboration of the San Antonio Bioscience and Medical Research Community
A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.
Latest Projects
The University of Texas at San Antonio
The University of Texas at San Antonio
Southwest Research Institute
Southwest Research Institute
The University of Texas at San Antonio
The University of Texas at San Antonio