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San Antonio Medical Foundation

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Top viewed research performed by San Antonio Bioscience Organizations

CD40 regulation of acute virus infection

The major goal of this project is to elucidate the role of virus-induced events in CD40 signaling in macrophages and the importance of these signals for controlling filovirus infection. Work will use both existing and new virus stocks to challenge the selected tissues and include infection assays, cytokine/chemokine profiling, virus inactivation, analysis of infection efficiencies, and mice virus challenge.

Texas Biomedical Research Institute
Shtanko, Olena
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A Multinational, Multicenter, Randomized, Phase 3 Study Of Tesetaxel Plus A Reduced Dose Of Capecitabine Versus Capecitabine Alone In Patients With HER2 Negative, Hormone Receptor Positive, Locally Advanced Or Metastatic Breast Cancer Previously Treated W

This is a multinational, multicenter, randomized, open-label, parallel-group Phase 3 study. The primary objective is to compare the efficacy of tesetaxel plus a reduced dose of capecitabine versus the approved dose of capecitabine alone based on progression-free survival (PFS), as assessed by an Independent Radiologic Review Committee (IRC), in patients with HER2 negative, HR positive MBC previously treated with a taxane in the neoadjuvant or adjuvant setting.

Brooke Army Medical Center
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