Facilitated By

San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

ROLE OF THE SEROTONIN TRANSPORTER AND ORGANIC CATION TRANSPORTER 3 IN SEROTONERGIC MODULATION OF EMOTION-REGULATING CIRCUITRY

Dysfunctional serotonergic neuromodulation in mood-regulating circuits underlies many psychiatric diseases, thusunderstanding regulation of serotonin (5-HT) transmission is of fundamental importance. The 5-HT transporter(SERT) clears 5-HT from extracellular fluid with high-affinity, and is considered a primary controller of the strengthand duration of 5-HT signaling. Our studies have revealed that organic cation transporter 3 (OCT3), a low-affinity,but high-capacity transporter of monoamines, plays a critical role in 5-HT clearance as well.

UT Health San Antonio
Daws, Lynette C
More Info
A Phase IIb, Double Blind Randomized, Controlled Clinical Trial, To Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients with Non-Alcoholic Steatohepatitis (NASH)

This is a multicenter, Phase IIb, randomized, double blind, placebo-controlled study designed to evaluate the efficacy and safety of two Aramchol doses in subjects that are 18 to 75 years of age, with Non-Alcoholic Steatohepatitis (NASH) confirmed by liver biopsy performed in a period of 6 months before entering the study, with overweight or obesity and who are pre diabetic or type II diabetic.

Eligible subjects will be enrolled into three treatments arms: Aramchol 400 and 600 mg tablets and placebo tablets in ratio 2:2:1.

Brooke Army Medical Center
Email for information
More Info