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San Antonio Medical Foundation

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Glioblastoma (GBM) is the most common and most aggressive of the primary malignant brain tumor in adults,with a median overall survival of 19.6 months following multi-modality therapy. The main limiting factor indelivering a tumoricidal radiation dose is the toxicity to surrounding brain. Therapeutic radionuclides, due to ashort tissue path and differences in radiobiology, have the potential to extend the therapeutic window for radiationin GBM.

UT Health San Antonio
Brenner, Andrew

This proposal combines a team with expertise in aging, tumor immunology, tumor immunotherapy, specificgenetically modified animal models and early phase clinical trials with a computational team having greatexpertise in analyzing and modeling aging of the immune system.

UT Health San Antonio
Curiel, Tyler J