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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating The Safety And Efficacy Of Obeticholic Acid In Subjects With Nonalcoholic Steatohepatitis

The primary objective of this study is to evaluate the effect of OCA compared to placebo on histological improvement in nonalcoholic steatohepatitis (NASH) by assessing the following primary endpoints using NASH Clinical Research Network (CRN) scoring criteria: Improvement in fibrosis by at least 1 stage with no worsening of NASH, or Resolution of NASH with no worsening fibrosis

Brooke Army Medical Center
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Taccalonolides: Mechanisms of Action and Cellular Resistance

Microtubule stabilizers are valuable drugs used in the treatment of cancer. The focus of this project is a new class of plant-derived microtubule stabilizers, the taccalonolides. The taccalonolides have distinct effects on interphase microtubule bundling, mitotic spindle morphology and mitotic signaling pathways. Potent new taccalonolides have been identified for the first time and they robustly polymerize purified tubuli indicating a direct interaction with tubulin/microtubules.

UT Health San Antonio
Mooberry, Susan L
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