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Top viewed research performed by San Antonio Bioscience Organizations

Perturbation of antigen-specific T cell responses in latent TB/SIV co-infection

The major goal is to identify antigen-specific T cell responses in macaques with LTBI and SIV co-infection. Here we have infected some animals with Mtb to develop LTBI, while others naturally progress to ATB. Further, some of the animals have been co-infected with SIV (n=6) and 4 of which reactivated and 2 didn't. In the years to come we will focus on generating more LTBI, ATB, R, NR animals and also perform SIV ART treatment. Eventually antigen-specific responses to ESAT-6, CFP-10, and CW will be evaluated in the peripheral as well as lung samples. Role: MPI

Texas Biomedical Research Institute
Kaushal, Deepak
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37th Annual Symposium on Nonhuman Primate Models for AIDS

HIV is a major worldwide challenge that remains to be solved, and there is a continuous need to identify improved preventative and therapeutic interventions. This annual symposium provides an environment that promotes the exchange of ideas and perspectives, and fosters new collaborations, especially between junior and senior members of the research community.

Texas Biomedical Research Institute
Giavedoni, Luis D.
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