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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

COGNITIVE ADAPTATION TRAINING: EFFECTIVENESS IN REAL-WORLD SETTINGS AND MECHANISMS OF ACTION (CAT-EM)

Schizophrenia remains one of the most disabling conditions world-wide with an economic burden thatexceeded $155 billion dollars in fiscal year 2013 alone. Despite existing medication and community treatment,many individuals with this diagnosis continue to have poor outcomes and struggle toward recovery.

UT Health San Antonio
Velligan, Dawn I
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Regulation of the Unfolded Protein Response After Acute Brain Injury

The proposed research investigates novel molecular targets and processes that promise to minimize brain damage after cerebral ischemic stroke (CIS) and traumatic brain injury (TBI). Current therapeutic strategies to combat acute brain injuries have been largely unsuccessful. We discovered that the Ca2+ dependent phosphatase calcineurin (CN) can bind to PERK, a stress sensor in the endoplasmic reticulum (ER), increases its auto-phosphorylation and enhance a cellular process called the Unfolded Protein Response (UPR).

UT Health San Antonio
Lechleiter, James D
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