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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

A Randomized, Double-Blind Phase 3 Study of Vadastuximab Talirine (SGN-CD33A) Versus Placebo in Combination withAzacitidine or Decitabine in the Treatment of Older Patients with Newly Diagnosed Acute Myeloid Leukemia

This is a randomized, double-blind, placebo-controlled phase 3 study designed to compare the OS between patients treated with HMA plus vadastuximab talirine (experimental arm) versus patients treated with HMA plus placebo (comparator arm). Patients will be randomized in a 1:1 manner to one of the study arms. Investigators may select either HMA (azacitidine or decitabine).

Brooke Army Medical Center
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Heme and Protein Radicals

A distinguishing trait of heme enzymes is that a high-valent iron-oxo species is the common oxidant for mediating a remarkable array of oxidation reactions. However, the conundrum is that each enzyme in general only promotes a specific type of reaction. How the reaction type is determined after formation of the key oxidant remains to be an unsolved question. Answers to this question have implications for our fundamental understanding of enzyme catalysis as well as de novo enzyme design and protein engineering.

The University of Texas at San Antonio
Liu, Aimin; Wherritt, Daniel; Griffith, Wendell; Schanze, Kirk; McHardy, Stanton
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