The goal of this project is to optimize the culture and purification conditions for production of recombinant Coccidioides antigens using a fungal expression system. We have created two transformed Uncinocarpus reesii clones (CTS1ur and BGL2ur) that can produce recombinant Coccidioides antigens (rCTSur and rBGL2ur), respectively. We will develop purification protocol to produce high yield of these two Coccidioides antigens for development of rapid diagnosis assays.
A Collaboration of the San Antonio Bioscience and Medical Research Community
A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.