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Malaria remains a significant contributor to the global burden of disease. In endemic regions, malaria mostlyaffects children. Older individuals are protected from disease by an immune response against the parasite?sblood stage. Eliciting a protective immune response in children by vaccination would significantly reducemalaria morbidity and mortality. Antibodies are a critical component of such protection. A strong correlationexists between antibodies against merozoite antigens and a reduction in malaria incidence.

UT Health San Antonio
Bunnik, Evelien M