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Top viewed research performed by San Antonio Bioscience Organizations


Novel model for studying PDAC using normal human pancreatic tissue For the past twenty years, the survival rate for many cancers has improved, but survival for pancreaticductal adenocarcinoma (PDAC) has not, due to lack of both early detection methods and effective treatments.Human PADC cancer cell lines have been widely used. However, such cell lines are far from original organtissue, and their highly unstable genome complicates interpretation.

UT Health San Antonio
Wang, Pei

Coxiella burnetii is an obligate intracellular Gram-negative bacterium that causes acute and chronic Q fever in humans. It is an understudied category B select agent and can be transmitted via aerosol. The existing formalin-inactivated phase I whole-cell vaccine (PIV) induces serious side effects in previously sensitized individuals and no vaccine is commercially available for prevention of human Q fever in the US. Therefore, creation of a safe and effective vaccine to prevent Q fever remains an important public health and national biosecurity goal.

The University of Texas at San Antonio
Zhang, Guoquan