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San Antonio Medical Foundation

A Collaboration of the San Antonio Bioscience and Medical Research Community

A first-of-its-kind initiative between public and private sector to catalog and highlight Bioscience research in the city of San Antonio and the surrounding areas.

Trending Research

Top viewed research performed by San Antonio Bioscience Organizations

HUMAN HYPOTHALAMIC NEURONAL EPIGENOMICS AND RISK FOR OBESITY

Translating information on genetic risk for body weight regulation into molecular mechanisms can have asignificant impact on intervention and therapies. We are seeking to identify genetic variation and theirmolecular mechanisms that influences obesity through direct effects on the hypothalamus as it is the brain hubthat regulates energy homeostasis and there is now considerable evidence for genetic influence to impact thisbrain region.

UT Health San Antonio
Lehman, Donna M
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DISSECTING THE INTERPLAY BETWEEN PROTEASOME DYSFUNCTION, PROTEOSTASIS AND ALZHEIMER'S DISEASE

Alzheimer's disease (AD) affects 5.5 million Americans producing cognitive deficits and mortality. Thereis no treatment for AD, thus, development of interventions to slow or reverse AD symptoms is a critical area ofresearch. Furthermore, AD is difficult to detect until substantial neurodegeneration has already occurred. Thisproposal investigates proteasome function both as an intervention to AD symptoms and as a tool for earlystage diagnosis in peripheral tissues. A key symptom of AD is proteostatic dysfunction.

UT Health San Antonio
Pickering, Andrew M
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