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Top viewed research performed by San Antonio Bioscience Organizations

Characterization of 2-oxindole forming heme enzyme in the biosynthetic pathway of maremycins

A2-oxindole forming heme enzyme. MarE. had been proposed as a fifth member pending structural validation.45 MarE is a functionally characterized monooxygenase that generates the oxindole moiety found in the biosynthetic pathways for maremycins (A - G). spirotryprostatin (A - B). and others. We will determine the crystal structure of MarE and revisit its catalytic function.

The University of Texas at San Antonio
Liu, Aimin
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A Multicenter, Randomized, Double-Blind, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients (NYHA Class II-IV) with Preserved Ejection Fraction

The purpose of this study is to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.

Brooke Army Medical Center
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