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Top viewed research performed by San Antonio Bioscience Organizations

Evaluation of the Platelet Derived Hemostatic Agent (PDHA) Stasix® for Dose-Response Efficacy in a Rabbit Model of Thrombocytopenia

Acute coagulopathy is a major complication affecting both soldiers and civilians sustaining traumatic injuries. Human Platelet Derived Hemostatic Agents (PDHAs) have been developed in an attempt to improve hemostatic capabilities for patients experiencing coagulopathies related to platelet deficit or dysfunction. These products are expected to be particularly vital to soldiers injured on the front lines, where medical facilities are not readily available. One PDHA currently being considered for use by the U.S.

Naval Medical Research Unit San Antonio (NAMRU-SA)
CDR Forest R. Sheppard, MD FACS, U.S. Navy
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Role of Dendritic Cells in Regulating T Cell-mediated Immunity Against Q Fever

Coxiella burnetii is an obligate intracellular Gram-negative bacterium that causes acute and chronic Q fever in humans. There is an urgent need to create a safe and effective vaccine for prevention of human Q fever. However, the mechanisms of vaccine-induced immunity against C. burnetii natural infection remain unclear. The long-term goal of this project is to develop a safe and effective vaccine against Q fever.

The University of Texas at San Antonio
Zhang, Guoquan
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