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Type 2 diabetes (T2D) afflicts nearly 30 million individuals in the US, with at least 50% suffering from neurologicalcomplications that comprise diabetic neuropathy (DN). The metabolic changes in T2D produce substantialperipheral nerve damage that manifests commonly as debilitating numbness and neuropathic pain. Progressionof the nerve damage often leads to loss of sensation that can compromise patients? ability to execute daily tasksand care for themselves, while also increasing risk of severe injury.

UT Health San Antonio
Lococo, Peter

The purpose of this study is to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.

Brooke Army Medical Center
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