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San Antonio Medical Foundation

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Top viewed research performed by San Antonio Bioscience Organizations


Exposure to gadolinium-based magnetic resonance imaging (MRI) contrast is a major risk factor in the acquisition of nephrogenic systemic fibrosis (NSF), a severely debilitating disease first recognized in patients with acute or chronic renal impairment. MRI contrast agents heretofore were considered safe in these patients and thus indiscriminately used. Gadolinium-based contrast agents remain a mainstay for MR imaging and alternatives are still lacking.

UT Health San Antonio
Wagner, Brent

In this multidisciplinary proposal we will use a nonhuman primate model of Parkinsons disease to study the reversibility of the beneficial effects of physical exercise and its impact on induced pluripotent stem cell (iPSC)-based therapy. We will investigate how exercise and iPSC-based cell therapy reinnervate the striatum and restore movement and gait by recruiting new neural networks as revealed by longitudinal multimodal imaging, behavioral and morphological analysis.

Texas Biomedical Research Institute
Marcel Daadi