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San Antonio Medical Foundation

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Migraine is a collection of neurological symptoms that include recurring, intense, throbbing headache pain thatcan last from 4 to 72 hours and affects millions of people. The discovery of the triptan drugs was a majorbreakthrough for the treatment of debilitating pain for many migraine sufferers. Unfortunately, repeated orprolonged use of triptans and other analgesic drugs (e.g. opioids, ergotamines) often results in production of aserious, disabling adverse effect known as medication overuse headache (MOH).

UT Health San Antonio
Berg, Kelly A

The major goal of this project, using a model of Kawasaki disease in mice, is to selectively turn off the FSTL-1 gene at different times during the onset and development of the disease, and evaluate if, and how, FSTL-1 affects the heart damage seen in Kawasaki disease in order to develop an effective treatment strategy for Kawasaki disease's long term effects.

Texas Biomedical Research Institute
Patterson, Jean