Cortical function is characterized by the dynamic interplay of two major forces: excitation and inhibition. A current belief is that dysfunction of inhibition. mediated by local GABAergic interneurons. leads to a wide range of neurological diseases such as epilepsy. autism. schizophrenia. PTSD. A well-established principle of the cortical circuit organization is that inhibition is local while excitation is both local and long-range; however. this ignores that inhibition may be long-range as well.
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The University of Texas at San Antonio
The University of Texas at San Antonio
The University of Texas at San Antonio
The University of Texas at San Antonio
The University of Texas at San Antonio
The University of Texas at San Antonio