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Generalization, the tendency to respond in similar ways in different situations, can be adaptive or maladaptive, depending on the context. For example, generalizing fear of a real threat to other similar dangerous contexts can be important for survival; conversely, displaying fear in safe environments is detrimental. The ventral hippocampus (VH) is in a key position to modulate valence and provide contextual information that allows for selective or generalized responses. Yet little is known about how this area modulates these behaviors.

The University of Texas at San Antonio
Muzzio, Isabel; Apicella, Alfonso