There is currently no efficient vaccine developed to prevent infection by the Human Immunodeficiency Virus (HIV), the agent responsible for Acquired Immunodeficiency Syndrome (AIDS). Classic vaccine strategies, such as the use of live attenuated viruses, where the immune system is stimulated by exposure of the host organism to non infectious viral particles, have led to safety issues in the case of HIV. We propose to develop a new vaccine strategy that elicits a long-term immunity against HIV infection at the site of entry of the virus in the case of mucosal infection.
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The University of Texas at San Antonio
The University of Texas at San Antonio
Southwest Research Institute
Southwest Research Institute
The University of Texas at San Antonio
The University of Texas at San Antonio