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San Antonio Medical Foundation

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Saliva is an important defense mechanism for protecting oral health. Salivary gland (SG) hypofunctionresults in uncontrolled and severe oral diseases that lead to severely compromised quality of life. SGsare highly differentiated and have little regenerative capacity once they are destroyed by therapy ordisease (e.g. radiation therapy or autoimmune Sjgren?s syndrome). Therefore, the development ofstrategies for preserving or regenerating the secretory function of SGs is essential for successfulmanagement of these patients.

UT Health San Antonio
Yeh, Chih-Ko

Increasing evidence supports the role of arsenic exposure in the development of diabetes. This study will evaluate the role of arsenic exposure and metabolism and their interaction with genetic markers in the development of diabetes in American Indian communities. This study can provide insight into the arsenic- diabetes relationship and inform public health recommendations for arsenic levels in drinking water and food.

Texas Biomedical Research Institute
Cole, Shelley A.