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San Antonio Medical Foundation

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Ewing's sarcoma is a childhood/young adult cancer. Unfortunately, many Ewing's sarcoma cancer patients are first diagnosed when the cancer cells are already spreading throughout the body, and these patients have a very poor prognosis. Therefore, identifying novel means to improve the effectiveness of the standard treatment of this cancer, a cocktail of drugs that includes etoposide, would be of immediate benefit. This proposal will provide the basis for novel strategies in the treatment of human cancer.

UT Health San Antonio
Bishop, Alexander James

The current therapy for diabetes patients is suboptimal as many endure complications leading to blindness, kidney failure, amputations, heart failure and stroke. We propose to develop unique stem cells engineered from skin or blood cells of patients and coaxed into insulin producing cells, which will be then microencapsulated and grafted under the skin of a patient. This proposal will help support the initial testing in the baboon model of diabetes developed at Texas Biomed.

Texas Biomedical Research Institute
Daadi, Marcel