Facilitated By

San Antonio Medical Foundation

Mapping Drug Resistance Genes in Plasmodium falciparum

Texas Biomedical Research Institute


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Principal Investigator(s)
Timothy JC Anderson
Collaborating Institutions
Shoklo Malaria Research Institute - Thailand
Funded by
National Institutes of Health
Research Start Date

Artemisinin combination therapy (ACT) is the main treatment for Plasmodium falciparum malaria: the success of this treatment has rolled back malaria and renewed interest in malaria elimination. Slow clearance of parasites following ACT treatment of patients in SE Asia has lead to concern about the spread of resistance. This proposal aims to identify the genes that underlie slow clearance to better understand the evolution and biochemical basis of this trait.

Collaborative Project
Basic Research
Infectious Disease