Facilitated By

San Antonio Medical Foundation

Impact of Tat-binding Cellular LncRNAs on HIV replication

Texas Biomedical Research Institute

 

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Principal Investigator(s)
Smita Kulkarni
Funded by
NIH
Research Start Date
Status
Active

The goal is to investigate the molecular basis of the functional impact of HIV-Tat protein binding cellular LncRNAs on HIV replication. Outcomes from the study outlined in this proposal will likely provide new functional insights into how the interaction between cellular LncRNAs and HIV proteins contributes to HIV pathogenesis and host defense, and identify novel molecular mechanisms of gene regulation, as well as therapeutic targets.

Collaborative Project
Basic Research
Drug Discovery
Infectious Disease