Facilitated By

San Antonio Medical Foundation

Impact of tuberculosis on the development and function of the immune system in SIV-infected infants

Texas Biomedical Research Institute

 

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Principal Investigator(s)
Kaushal, Deepak
Collaborating Institutions
Tulane University
Funded by
National Institutes of Health
Research Start Date
Status
Active

19-036 This proposal is designed to determine the immunological changes induced by SIV Infection that contributes to the increased severity of mtb in infants, and the effects of early antiretroviral therapy (ART) and Immunotherapy (IDO-inhibitor treatment) on both infections by comparing viral/bacterial burdens, innate, adaptive, and pathogen specific cellular and humoral immune responses, pulmonary pathology, latency, reservoirs, and Disease Progression. Role: Sub-PI

Collaborative Project
Basic Research
Disease Modeling
Infectious Disease