CD40 regulation of acute virus infection
Principal Investigator(s)
Shtanko, Olena
Collaborating Institutions
University of Iowa
Funded by
National Institutes of Health
Research Start Date
Status
Active
The major goal of this project is to elucidate the role of virus-induced events in CD40 signaling in macrophages and the importance of these signals for controlling filovirus infection. Work will use both existing and new virus stocks to challenge the selected tissues and include infection assays, cytokine/chemokine profiling, virus inactivation, analysis of infection efficiencies, and mice virus challenge.