Clinical Evaluation Of Decellularized Nerve Allograft With Autologous Bone Marrow Stem Cells To Improve Peripheral Nerve Repair And Functional Outcomes
Principal Investigator(s)
Email for information
Funded by
HJF
Research Start Date
Status
Active
This study is a prospective, multi-center, proof of principle, phase I human safety study (n=12) evaluating the sequential treatments of the Avance Nerve Graft, a commercially available decellularized processed peripheral nerve allograft, with autologous Bone Marrow Aspirate Concentrate (BMAC), a source of stem cells, for the repair of peripheral nerve injuries of up to 7 cm in length. The purpose of this study is to establish a knowledge product, evaluating the safety profile of the Avance Nerve Graft, followed by the application of BMAC to support further investment into the promising area of using stem cells in conjunction with scaffolds.
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