Facilitated By

San Antonio Medical Foundation

Copy Number Variation in Malaria Parasite

Texas Biomedical Research Institute


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Principal Investigator(s)
Anderson, Timothy J. C.
Collaborating Institutions
University of Notre Dame
Funded by
Research Start Date

Gene copy number variation (CNV) is ubiquitous in eukaryotic genomes and the resultant dosage changes can play an important role in determining phenotype. We aim to define the extent, evolutionary dynamics and functionality of CNV in the malaria parasite genome (Plasmodium falciparum). To achieve this we will use comparative genomic hybridization (cGH) which provides an efficient tool for assaying both CNV and single nucleotide polymorphism (SNP) and is particularly effective in haploid genomes.

Collaborative Project
Infectious Disease