Harvard Study
Principal Investigator(s)
Chagoy
Research Start Date
Status
Active
To characterize immune-inflammatory and coagulatory response blood from traumatic hemorrhage and burn injury patients requiring mass transfusion. To characterize functional and structural changes of normal blood cellular components from healthy donors when incubated with plasma collected at different timepoints after injury from traumatic hemorrhaged patients. To investigate the effects of adding tranexamic acid, Eculizumab (anti-C5 mAb), and/or C1inhibitor on function and structural changes of normal blood cells incubated with plasma from traumatic hemorrhaged patients
The views expressed are those of the authors and do not reflect the official views or policy of the Department of Defense or its Components. Where applicable, the voluntary fully informed consent of the subjects used in this research was obtained as required by 32 CFR 219 and DODI 3216.02_AFI 40-402