Impact of tuberculosis on the development and function of the immune system in SIV-infected infants
Principal Investigator(s)
Kaushal, Deepak
Collaborating Institutions
Tulane University
Funded by
National Institutes of Health
Research Start Date
Status
Active
19-036 This proposal is designed to determine the immunological changes induced by SIV Infection that contributes to the increased severity of mtb in infants, and the effects of early antiretroviral therapy (ART) and Immunotherapy (IDO-inhibitor treatment) on both infections by comparing viral/bacterial burdens, innate, adaptive, and pathogen specific cellular and humoral immune responses, pulmonary pathology, latency, reservoirs, and Disease Progression. Role: Sub-PI