Mechanism and Evolution of Filoviral Monoclonal Affinity Reagent Sandwich

Rapidly detecting viral signatures is important in diagnosing Marburg and Ebola viral disease to hasten quarantine, limit the spread of contagion, and contain an outbreak. We have discovered a group of llama derived antibodies that bind to highly conserved regions of a Filoviral polymer, thereby enabling sensitive detection of a broad range of these viruses. Our aim to is to develop these antibodies into streamlined tests designed to detect all Marburg and Ebola strains known and potentially those yet to emerge, helping to safeguard human health both now and into the future.