Texas Biomed Filovirus VLP Efficacy GP/NHP
Principal Investigator(s)
Patterson, Jean L.
Funded by
Battelle
Research Start Date
Status
Inactive
The mission of the TxBiomed component is to generate the Marburg virus and propagate it, determine the virus' consensus sequence, experimentally determine the LD50 of guinea pig adapted Angolan Marburg virus, and evaluate the immunogenicity and efficacy of Marburg and Ebola Zaire VLPs monovalent vaccines when administered in two different adjuvants to guinea pigs and Non-Human Primates.