Facilitated By

San Antonio Medical Foundation

Texas Biomed Filovirus VLP Efficacy GP/NHP

Texas Biomedical Research Institute


As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.

Principal Investigator(s)
Patterson, Jean L.
Funded by
Research Start Date

The mission of the TxBiomed component is to generate the Marburg virus and propagate it, determine the virus' consensus sequence, experimentally determine the LD50 of guinea pig adapted Angolan Marburg virus, and evaluate the immunogenicity and efficacy of Marburg and Ebola Zaire VLPs monovalent vaccines when administered in two different adjuvants to guinea pigs and Non-Human Primates.

Basic Research
Infectious Disease