Facilitated By

San Antonio Medical Foundation

UT Health SA COVID-19 Pilot Program: Role of the polybasic furin cleavage site sequence in SARS-CoV-2 biology and therapeutic implications

Texas Biomedical Research Institute


As one of the world’s leading independent biomedical research institutions, Texas Biomedical Research Institute is dedicated to advancing the health of our global community through innovative biomedical research.

Principal Investigator(s)
Ebrahimi, Diako
Collaborating Institutions
University of Texas Health Science Center San Antonio
Research Start Date

We aim to fully characterize mutational signatures of SARS-CoV-19 focusing on the furin cleavage site, determine the role of the GC-rich sequence and CpG sites within the furin cleavage site and develop neutralizing Abs to target the furin cleavage site.

Collaborative Project
Basic Research
Infectious Disease